VIETNAM NUTRITIONAL PORTAL
A cross-sectional study has been conducted in 210 pregnant women at 5 communes of Dai Tu district, Thai Nguyen province to determine the prevalence of vitamin D deficiency. Serum 25(OH) D was measured by HPLC method. Results: The prevalence of vitamin D deficiency 25(OH) D <50 nmol/L was 22.4%, among them: 21% had mild vitamin D deficiency and 1.4% had moderate vitamin D deficiency.
Journal of Food and Nutrition Sciences - Vol.12, No.1, Year 2016
(Link to the journal issue: https://tapchidinhduongthucpham.org.vn/index.php/jfns/issue/view/45)
Author: Thuy Nga TRAN, Van Thuy PHAM, Danh Tuyen LE
Abstract
A cross-sectional study has been conducted in 210 pregnant women at 5 communes of Dai Tu district, Thai Nguyen province to determine the prevalence of vitamin D deficiency. Serum 25(OH) D was measured by HPLC method. Results: The prevalence of vitamin D deficiency 25(OH) D <50 nmol/L was 22.4%, among them: 21% had mild vitamin D deficiency and 1.4% had moderate vitamin D deficiency. Prevalence of vitamin D insufficiency, 25(OH) D between 50-74.9 nmol/L, in pregnant women was 50.0%. Pregnant women who were not farmers had 72% increased risk for vitamin D deficiency (OR=0.28; 95% CI: 0.12-0.69; p<0.001). Singleton pregnant women had 1.58 times higher risk for vitamin D deficiency (OR=1.58; 95% CI: 1.16-2.15; p<0.01). Conclusions: Vitamin D deficiency and insufficiency are common among pregnant women. The prevention of micronutrient deficiency especially vitamin D deficiency should be promoted by appropriate interventions to improve the micronutrient status for pregnant women.
Keywords: Vitamin D deficiency, vitamin D insufficiency, pregnant women, north mountainous area
References
1. Smith GC (2004) First trimester origins of fetal growth impairment. Semin Perinatol. Feb; 28(1):41-50. Review.
2. Mahon P, Harvey N, Crozier S, Inskip H, Robinson S, Arden N, Swaminathan R, Cooper C, Godfrey K; SWS Study Group (2010). Low maternal vitamin D status and fetal bone development: cohort study. J Bone Miner Res. Jan;25(1):14-9.
3. Bodnar LM, Simhan HN, Powers RW, Frank MP, Cooperstein E, Roberts JM (2007). High prevalence of vitamin D insufficiency in black and white pregnant women residing in the northern United States and their neonates. J Nutr. 137(2):447-52.
4. Marwaha RK, Tandon N, Chopra S, Agarwal N, Garg MK, Sharma B, Kanwar RS, Bhadra K, Singh S, Mani K, Puri S (2011). Vitamin D status in pregnant Indian women across trimesters and different seasons and its correlation with neonatal serum 25-hydroxyvitamin D levels. Br J Nutr. 106(9):1383-9. Epub 2011 May 31.
5. Michael F. Holick, Binkley, Heike. Bischoff-Ferrari, Catherine M. Gordon, Hanley, Robert P. Heaney, M. Hassan Murad, and Connie M. Weaver (2011). Evaluation, Treatment, and Prevention of Vitamin D Deficiency: An Endocrine Society Clinical Practice Guideline. Journal of Clinical Endocrinology & Metabolism, July 2011, 96(7): 1911–1930.
6. Hien VT, Lam NT, Skeaff CM, Todd J, McLean JM, Green TJ (2012). Vitamin D status of pregnant and non-pregnant women of reproductive age living in Hanoi City and the Hai Duong province of Vietnam. Matern Child Nutr. Oct;8(4):533-9.
7. Charatcharoenwitthaya N, Nanthakomon T, Somprasit C, Chanthasenanont A, Chailurkit LO, Pattaraarchachai J, Ongphiphadhanakul B (2013). Maternal vitamin D status, its associated factors and the course of pregnancy in Thai women. Clin Endocrinol (Oxf). 2013 Jan;78(1):126-33.
8. Halicioglu O, Aksit S, Koc F, Akman SA, Albudak E, Yaprak I, Coker I, Colak A, Ozturk C, Gulec ES (2012). Vitamin D deficiency in pregnant women and their neonates in spring time in western Turkey. Paediatr Perinat Epidemiol. 2012 Jan;26(1):53-60.
9. Shao H, Tao M, Fan Y, Jing J, Lu J (2012). Vitamin D levels and other factors related to bone mineral density during pregnancy. Aust N Z J Obstet Gynaecol. 2012 Dec;52(6):571-5.
Nghiên cứu cắt ngang mô tả, trên 210 phụ nữ có thai tại 5 xã huyện Đại Từ, một huyện miền núi phía Tây Bắc tỉnh Thái Nguyên nhằm tìm hiểu tình trạng thiếu vitamin D ở phụ nữ có thai và một số yếu tố liên quan. Định lượng nồng độ vitamin D trong huyết thanh bằng phương pháp HPLC.
Tạp chí Dinh dưỡng & Thực phẩm - Tập 12, Số 1, Năm 2016
(Link số tạp chí: https://tapchidinhduongthucpham.org.vn/index.php/jfns/issue/view/45)
Tác giả: Trần Thúy Nga, Phạm Vân Thúy, Lê Danh Tuyên
Tóm tắt
Nghiên cứu cắt ngang mô tả, trên 210 phụ nữ có thai tại 5 xã huyện Đại Từ, một huyện miền núi phía Tây Bắc tỉnh Thái Nguyên nhằm tìm hiểu tình trạng thiếu vitamin D ở phụ nữ có thai và một số yếu tố liên quan. Định lượng nồng độ vitamin D trong huyết thanh bằng phương pháp HPLC. Hàm lượng vitamin D < 50 nmol/L phản ánh tình trạng thiếu vitamin D và hàm lượng vitamin D từ 50-74,9 nmol/L phản ánh tình trạng vitamin D không đủ/ thấp. Kết quả: Tỷ lệ thiếu vitamin D là 22,4% trong đó, 21% phụ nữ có thai thiếu vitamin D ở mức độ nhẹ; 1,4% thiếu vitamin D ở mức độ vừa. Tỷ lệ vitamin D không đủ/ thấp ở phụ nữ có thai là 50%. Thiếu vitamin D ở phụ nữ có thai có liên quan chặt chẽ với nghề nghiệp (OR=0,28; 95% CI: 0,12-0,69; p<0,001); chưa sinh con lần nào (OR=1,58; 95% CI: 1,16-2,15; p<0,01). Kết luận: Thiếu vitamin D và vitamin D không đủ/ thấp là vấn đề phổ biến ở phụ nữ có thai. Phòng chống thiếu vi chất, đặc biệt là thiếu vitamin D tại cộng đồng cần được đẩy mạnh bằng các can thiệp phù hợp nhằm cải thiện tình trạng vi chất dinh dưỡng cho phụ nữ có thai.
Từ khóa: Thiếu vitamin D, vitamin D thấp, phụ nữ có thai, miền núi phía Bắc
Tài liệu tham khảo
1. Smith GC (2004) First trimester origins of fetal growth impairment. Semin Perinatol. Feb; 28(1):41-50. Review.
2. Mahon P, Harvey N, Crozier S, Inskip H, Robinson S, Arden N, Swaminathan R, Cooper C, Godfrey K; SWS Study Group (2010). Low maternal vitamin D status and fetal bone development: cohort study. J Bone Miner Res. Jan;25(1):14-9.
3. Bodnar LM, Simhan HN, Powers RW, Frank MP, Cooperstein E, Roberts JM (2007). High prevalence of vitamin D insufficiency in black and white pregnant women residing in the northern United States and their neonates. J Nutr. 137(2):447-52.
4. Marwaha RK, Tandon N, Chopra S, Agarwal N, Garg MK, Sharma B, Kanwar RS, Bhadra K, Singh S, Mani K, Puri S (2011). Vitamin D status in pregnant Indian women across trimesters and different seasons and its correlation with neonatal serum 25-hydroxyvitamin D levels. Br J Nutr. 106(9):1383-9. Epub 2011 May 31.
5. Michael F. Holick, Binkley, Heike. Bischoff-Ferrari, Catherine M. Gordon, Hanley, Robert P. Heaney, M. Hassan Murad, and Connie M. Weaver (2011). Evaluation, Treatment, and Prevention of Vitamin D Deficiency: An Endocrine Society Clinical Practice Guideline. Journal of Clinical Endocrinology & Metabolism, July 2011, 96(7): 1911–1930.
6. Hien VT, Lam NT, Skeaff CM, Todd J, McLean JM, Green TJ (2012). Vitamin D status of pregnant and non-pregnant women of reproductive age living in Hanoi City and the Hai Duong province of Vietnam. Matern Child Nutr. Oct;8(4):533-9.
7. Charatcharoenwitthaya N, Nanthakomon T, Somprasit C, Chanthasenanont A, Chailurkit LO, Pattaraarchachai J, Ongphiphadhanakul B (2013). Maternal vitamin D status, its associated factors and the course of pregnancy in Thai women. Clin Endocrinol (Oxf). 2013 Jan;78(1):126-33.
8. Halicioglu O, Aksit S, Koc F, Akman SA, Albudak E, Yaprak I, Coker I, Colak A, Ozturk C, Gulec ES (2012). Vitamin D deficiency in pregnant women and their neonates in spring time in western Turkey. Paediatr Perinat Epidemiol. 2012 Jan;26(1):53-60.
9. Shao H, Tao M, Fan Y, Jing J, Lu J (2012). Vitamin D levels and other factors related to bone mineral density during pregnancy. Aust N Z J Obstet Gynaecol. 2012 Dec;52(6):571-5.